Aspergillus nidulans—Natural Metabolites Powerhouse: Structures, Biosynthesis, Bioactivities, and Biotechnological Potential

نویسندگان

چکیده

Nowadays, finding out new natural scaffolds of microbial origin increases at a higher rate than in the past decades and represents an auspicious route for reinvigorating pool compounds entering pharmaceutical industries. Fungi serve as depository fascinating, structurally unique metabolites with considerable therapeutic significance. Aspergillus genus one most prolific genera filamentous fungi. nidulans Winter G. is well-known plentiful source bioactive abundant structural diversity, including terpenoids, benzophenones, sterols, alkaloids, xanthones, polyketides, many which display various bioactivities, such cytotoxicity, antioxidant, anti-inflammatory, antiviral, antimicrobial activities. The current work targeted to survey reported literature on A. nidulans, particularly its metabolites, biosynthesis, addition recent reports biotechnological potential. From 1953 till November 2022, relying stated data, 206 were listed, more 100 references.

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ژورنال

عنوان ژورنال: Fermentation

سال: 2023

ISSN: ['2311-5637']

DOI: https://doi.org/10.3390/fermentation9040325